Showing posts with label heart. Show all posts
Showing posts with label heart. Show all posts

February 07, 2011

Risk Factors for Heart Disease in People with Lupus

February is American Heart Month. Heart disease is a major complication of lupus and is now a leading cause of death among people with lupus. Today, I thought I'd share with you a research summary from a 2010 research eNewsletter about lupus and the heart.

Although it is known that people with lupus are at greater risk for coronary heart disease (CHD), very little is known about which people with lupus really are at risk and which are not. This study confirms certain “classic” risk factors for CHD like high cholesterol or blood pressure, smoking, and a family history of CHD, as well as some lupus-related characteristics (i.e., azathioprine treatment, high creatinine levels), which might increase CHD risk.

Read more>> 

February 12, 2010

Share Your Heart. Send an eCard this Valentine’s Day.

It’s Heart Health Month, so warm a heart this Valentine’s Day by sending an eCard to someone you care about.

The Lupus Foundation of America's Valentine's Day eCards will help you spread messages of affection and friendship while helping to increase awareness of lupus.

And they're so simple to use: fill in a few fields; select an eCard design; and click send. You can even personalize your subject line, and include your own special message.

Share your heart to those living with lupus by sending your eCard today.

February 11, 2010

Learn How Lupus Can Affect Your Cardiopulmonary (Heart & Lungs) System

Lupus is an autoimmune disease that can affect almost any part of your body, most often your joints, skin, kidneys, heart, lungs, blood, or brain.

Your heart, blood vessels, and lungs make up your cardiovascular/pulmonary network: "cardio" refers to the heart, "vascular" refers to the arteries, veins, and capillaries, and "pulmonary" refers to the lungs. Your blood circulates through this vast system, transporting oxygen and other elements needed for your cells and tissues to function properly. Cardiologists are the physicians who specialize in the heart. Pulmonologists are the physicians who specialize in the lungs.

February is Heart Health Month

As such, the Lupus Foundation of America would like to further educate people living with lupus about heart disease.

Heart disease is a major complication of lupus and is now a leading cause of death among people with lupus. Blood tests, chest X-rays, an electrocardiogram (EKG), or an echocardiogram may be used to find out if you have a heart condition caused by lupus.

Learn more about how lupus can affect your heart & lungs.

February 03, 2010

Updated Guidelines for Cardiovascular Health for Women

You know that heart health is important, but when you’re juggling work and home life, keeping heart healthy through diet and exercise can be tough. For people with lupus, especially women, those little slips can spell big trouble.

Lupus and its treatment often create problems, says Amy Kao, M.D., M.P.H., assistant professor of medicine at the University of Pittsburgh’s Lupus Center of Excellence. "People with lupus may be more likely to be physically inactive or develop excessive weight gain from steroids," she says. "Lupus itself can cause increased cardiovascular-disease risks, such as hypertension -- especially among those with lupus nephritis."

Learn Heart-Healthy Do's and Don'ts.

February 01, 2008

Lupus Foundation of America Observes February as National Heart Month

Morning everyone ... it's a rainy, dreary day here in the nation's capital. Lots to cover today so my intro will be brief. Just wanted to say how absolutely great it is that LOST is back on TV! It was worth the 8 month wait.

Have a great weekend.

Until next time, Wick

Heart Disease is a Major Complication of Lupus - February is National Heart Month

Heart disease is a major complication of lupus and is now a leading cause of death among people living with autoimmune disease. Individuals with lupus are at increased risk for cardiovascular disease (CVD), which involves hardening of the arteries and can lead to heart attacks or strokes later in life. As the nation observes February as “National Heart Month,” the Lupus Foundation of America is calling attention to this serious complication of lupus, an autoimmune disease that affects an estimated 1.5 - 2 million Americans.

Lupus is a chronic (lifelong) disease in which the immune system fails to tell the difference between foreign invaders, such as viruses and bacteria, and the body’s own cells. The immune system then produces auto-antibodies (“auto” means “self”) which mistakenly attack healthy tissue. These auto-antibodies cause inflammation, pain and damage to various parts of the body, including the heart, lungs, kidneys and brain.

Several studies have provided evidence that inflammation plays a role in heart disease. Inflammation causes a build-up of fatty deposits called plaque within coronary arteries, blood clots, and blockage of blood vessels within the heart -- placing one at increased risk for heart attack.

As the outlook for people with lupus has improved significantly over the past few decades, heart disease and other cardiac problems have surfaced as the most serious long-term risk for people suffering from lupus. Several decades ago, when lupus patients died shortly after developing lupus, the cause of death was often attributed to undiagnosed and untreated lupus. However, when patients lived for years after their diagnosis, the main cause of death changed to atherosclerosis, which occurs when cholesterol and other fatty deposits block the passageways where blood flows to the heart.

In studies that compared a group of women with lupus to a group of healthy women, researchers found that the lupus patients were more likely to have traditional risk factors for heart disease, such as diabetes and hypertension. In addition, these women had an earlier onset of menopause, and had higher levels of unsafe blood fats, including triglycerides and low-density lipoprotein (LDL) cholesterol. These factors are all exacerbated by the inflammation caused by lupus and contribute to the increased risk of coronary heart disease and accelerated atherosclerosis.

However, these factors alone do not fully account for the increased risk. Several factors more specifically related to lupus are proposed to have considerable importance, including chronic inflammation, antibodies that attack proteins that regulate the blood vessels, and therapy, especially corticosteroid use. As a result, researchers suggest that lupus should be considered equivalent to coronary heart disease as a known risk for heart attacks and strokes.

Because concerns about coronary heart disease in lupus patients have increased dramatically, researchers are studying potential therapies to reduce these risks. These include developing treatments that incorporate cholesterol-lowering drugs and aspirin-therapy. Meanwhile, lupus patients can take well-known steps to help lower their risk: lose weight, stop smoking, lower blood pressure, and get moderate aerobic exercise.

How Lupus Affects the Heart

Pericarditis
The most common way that lupus affects the heart is through inflammation of the pericardium, the sac that surrounds your heart. The symptoms of pericarditis that you may experience are sharp pain in your chest and, occasionally, shortness of breath. Pericarditis usually does not damage your heart’s ability to function because it does not directly involve the heart tissue. However, inflammation that is chronic (long-lasting) can scar the heart tissue, which can interfere with the heart’s ability to pump blood.

Myocarditis
Lupus can cause inflammation of the myocardium, the muscle tissue of your heart. The symptoms are chest pain and an unexplained rapid or irregular heart beat. Myocarditis is often seen when there is inflammation in other muscles in the body.

However, myocarditis can be caused by viral, bacterial, and fungal infections. Because lupus itself creates an added risk for developing infections -- especially if you are taking certain immunosuppressive drugs -- you are at increased risk for this type of myocarditis.

Though serious heart muscle disease is not commonly caused by lupus, heart failure can occur if your heart does not have the strength to pump enough blood to the different tissues and organs.

Endocarditis
The endocardium is the tissue that lines the inner walls of your heart and the valves that separate the heart’s different chambers. Lupus can cause inflammation of the endocardium. Lupus endocarditis usually causes the surfaces of the heart valve to thicken or develop wart-like growths (lesions). These lesions can become infected, a condition called bacterial endocarditis. A lesion also could break off and travel to the brain to form a blood clot. Both of these possibilities are potentially very dangerous.

Coronary Artery Disease
The coronary arteries move blood to and from your heart. Over time, fatty molecules and other materials may attach to the walls of these blood vessels and form plaque, which makes the blood vessels narrower and restricts blood flow. This condition is known as atherosclerosis. A decrease in blood flow can cause angina (chest pain). However, if the blood flow to your heart is interrupted -- either by plaque or by a blood clot that develops when plaque breaks off -- you could be at risk for a heart attack.

When you have lupus you are at increased risk for coronary artery disease. This is partly because people with lupus have more risk factors, which may include:

  • hypertension from kidney disease or corticosteroid use
  • elevated cholesterol levels from corticosteroid use
  • type 2 diabetes from corticosteroid use
  • an inactive, sedentary lifestyle due to fatigue, joint problems, and/or muscle pain
However, even after taking these risk factors into account, people with lupus are more likely to develop atherosclerosis. You can help reduce your chances of heart attacks and other complications from coronary artery disease in several ways:

  • control the risk factors
  • control the lupus disease activity
  • talk to your doctor about reducing or stopping your corticosteroid use

Additional Information