August 11, 2008

T Cell Activation May Not Be Required in Lupus

Researchers at Yale University recently discovered a way that B cells can be activated in the absence of T cells. Many researchers had believed that T cell activation of B cells was required to produce auto-antibodies, or antibodies that target “self,” causing autoimmune diseases, like lupus.

While the concept of B cells being activated without help from T cells is not totally new, this study may give some insight into why therapies that target T cells have not worked in past studies on lupus.

Read the Yale University release.

1 comment:

AlisonH said...

Any word on how the studies have been coming along--are they past Level 1 yet?--re sibling-to-lupus patient transplants of blood stem cells?