
The story also features LPGA pro golfer and Stanford University women’s assistant golf team coach Salimah Mussani, who has lupus.
The story highlights the promising research underway to understand more about lupus and develop new, safe and effective treatments for the unpredictable and potentially fatal autoimmune disease. It has been more than 40 years since a new drug was approved by the U.S. Food and Drug Administration (FDA) specifically for lupus.
Watch the KGO story about lupus.
About Dr. Utz’s LFA Research Grant -- "Proteomic Studies in Systemic Lupus Erythematosus"
Lay Abstract:
Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease that can progressively damage multiple organs. The pathophysiology of SLE involves antibody formation against self-molecules, including those directed against RNA and DNA. By employing several mouse models of SLE, this proposal will test the hypothesis that the initiation and progression of autoantibody production and end organ disease in SLE requires interferon signaling through three different intracellular proteins called IFNAR-2, STAT-1, and IRF-9. The results can be rapidly translated to the clinic by identifying new targets for drug development, and by discovering novel biomarkers for SLE.
About Salimah Mussani

View her page on the Stanford University website
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